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Long Non-Coding RNAs (Hardback)
Function, Mechanisms, and Applications
Imprint: IntechOpen
Series: Genetics
Pages: 214
ISBN: 9781836344797
Published: 2nd July 2025
Script Academic & Professional
Series: Genetics
Pages: 214
ISBN: 9781836344797
Published: 2nd July 2025
Script Academic & Professional
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LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.
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